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despite its relatively recent approval by the food and drug administration and the guideline recommendations, the therapeutic use of digoxin is declining in patients with heart failure likely the result of several factors.

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digoxin when micardis was co-administered with digoxin, median increases in digoxin peak plasma concentration 49 and in trough concentration 20 were observed.

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there are many other medicines that can interact with digoxin.

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gastrointestinal reactions hepatitis, hepatic failure, pancreatitis, bloody diarrhea, impaired folic acid absorption, impaired digoxin absorption, stomatitis, diarrhea, abdominal pains, and neutropenic enterocolitis.

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digoxin – in subjects who had received 21 days of 40 mg day citalopram hbr tablets, combined administration of citalopram hbr tablets and digoxin single dose of 1 mg did not significantly affect the pharmacokinetics of either citalopram or digoxin.

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